MLAB 1227: Coagulation


MLAB 1227: Coagulation

  • Dates: November 4- Dec. 15, 2024
  • Length of Course: 5 Weeks
  • Total Number of Hours: 48 Contact Hours

A course in coagulation theory, procedures, and practical applications. Includes quality control, quality assurance, safety and laboratory procedures which rely on commonly performed manual and/or semi-automated methods.

By the end of this course the student should be able to:

  • Apply principles of safety, quality assurance and quality control in coagulation.
  • Evaluate specimen acceptability and dispose of them in the appropriate biohazard containers.
  • Compare and contrast coagulation processes under normal and abnormal human conditions.
  • Perform basic laboratory Coagulation analysis
  • Evaluate laboratory test results and correlate with patient conditions(s).
  • Demonstrate compliance with OSHA safety regulations for blood –borne pathogens.

Please print the MLAB 1227 Syllabus and bring it to class.

Keohanne, Elaine M., Preston, Michelle M., Mirza, Kamran M., and Walenga Jeanine M., Rodak’s Hematology:
Clinical Principles and Applications, Seventh Edition, Elsevier, ISBN 978-0-323-93607

Quiz 1In class Covers Chapters 11 (Platelets) and  35 (Normal Hemostasis)  Thursday, November 7, 2024
Quiz 2 Covers Chapter 42- section on the TEG & TEG video Opens: Wednesday, November 13, 2024 Closes: Sunday, November 17, 2024
Exam 1Remote Covers: Chapters 11 (Platelets), 35( Normal Hemostasis), 41( Lab Evaluation of Hemostasis), and 42 (Hemostasis & Coagulation Instrumentation)Labs: Pre-analytical issues and coagulation automation Opens: Friday, November 15, 2024 at 7 am Closes: Sunday, November 17, 2024 at 8 pm
Quiz 3In class Covers Chapter 37(Disorders of Platelets & Vasculature) Thursday, November 14, 2024
Quiz 4In class Covers Chapter 36(Disorders of Secondary Hemostasis) Wednesday, November 20, 2024
Quiz 5In class Covers Chapter 38 (Quantitative Disorders of Platelets) Thursday, November 21, 2024
Quiz 6 Covers Chapter 39 (Thrombotic Disorders and Lab Assessment)  Tuesday, November 26, 2024
Practical ExamOn Campus Covers all labs, including Coagulation Automation and Lab Testing in Coagulation PPTs EVC: Wednesday, December 4, 20249:00-11:00 amRoom 9209 RRC: Wednesday, December 4, 20244:00-6:00 pmRoom 3121.00
FinalOn Campus Covers all lecture material EVC: Thursday, December 5, 20249- 11 amRoom 2307 RRC: Thursday, December 5, 20243:30- 5:30 pmRoom 3121.00

Admission tickets (ATs) and Pre-labs (PLs) are due by 8:30 a.m on the day the material is covered.

Week of 10/28/2024

Topic N/A
Textbook N/A
Laboratory N/A
Assignment
  • Pre-Lab Assessment: Bleeding time. Found in Bb under the Assignments button in the Pre-Lab folder. Due 11/6/2024
  • Admission ticket: Overview of Hemostasis and Platelet Physiology. Found in Bb under Assignments button in the lecture admission tickets folder. Due 11/6/2024
  • Please review this tutorial of how the blood clots. ( 5 minutes)

11/6/2024

Lecture Topics
Textbook
  • Ch. 11, pp. 159-175
    • Platelet Production, Structure, and Function
  • Ch. 35, pp. 661-666
    • Normal Hemostasis
  • Ch. 41, pp. 811-817, 826-827 (thrombin time)
    • Laboratory Evaluation of Hemostasis
Laboratory
Assignment

11/7/2024

Lecture Topics
Textbook
  • Ch. 35, pp. 666-673
    • Normal Hemostasis
  • Ch. 41, pp. 821-824 (PT)
    • Laboratory Evaluation of Hemostasis
Laboratory
Assignment
  • Pre-Lab Assessment: Hemostasis Testing; found in Bb under Assignments button in the lecture admission tickets folder. Due 11/13/2024
  • Admission ticket: Fibrinolysis and Physiologic Hemostasis; found in Bb under Assignments button in the lecture admission tickets folder. Due 11/13/2024
  • Watch the video “Warfarin” (15 minutes)

11/13/2024

Lecture Topics
Textbook
  • Ch. 35, pp. 676-683
    • Normal Hemostasis
  • Ch. 42, pp. 841-854, 855-857 (Platelet Function Testing)
    • Hemostasis and Coagulation Instrumentation
Laboratory
Assignment
  • Watch the Hemostasis, Coagulation, and Fibrinolysis video. (4 minutes)
  • Pre-Lab Assessment: aPTT; found in Bb under the Assignments button in the Pre-Lab folder. Due 11/14/2024
  • Admission ticket: Primary Disorders; found in Bb under assignments button in the lecture admission tickets folder. Due 11/14/2024
  • Homework: TEG Video and Quiz; Review the video here and take the TEG quiz found in Blackboard, under the Exam button, in the “Exams/Quiz” folder in the “Quizzes” folder. Due 11/17/2024
  • Handout: Diagnostic Approach to Bleeding

11/14/2024

Lecture Topic
Textbook
  • Ch. 37, pp. 713-729
    • Qualitative Disorders of Platelets and Vasculature
  • Ch. 41, pp. 824-826 (PTT)
    • Laboratory Evaluation of Hemostasis
Laboratory
Assignment
  • Pre-Lab Assessment: Fibrinogen; found in Bb under the Assignments button. Due 11/20/2024
  • Admission ticket: Secondary Disorders; found in Bb under assignments button. Due 11/20/2024
  • Homework: Inherited Platelet DefectsDue 11/17/2024
    • Navigate to the “Dropbox” in Bb, select the “Homework” folder, upload assignment.
  • Watch the video “Heparin” (14 minutes)
  • Watch the video “Heparin vs. Warfarin” (12 minutes.)

11/20/2024

Lecture Topic
Textbook
  • Ch. 36, pp. 686-707
    • Hemorrhagic Disorders and Lab Assessment
  • Ch. 39, pp. 775-778 (DIC)
    • Laboratory Evaluation of Hemostasis
Laboratory
Assignment
  • TBA

11/21/2024

Topic
Textbook
  • Ch. 38, pp. 734-755
    • Quantitative Disorders of Platelets:
    • Thrombocytopenia and Thrombocytosis
Laboratory
Assignment
  • Admission ticket: Thrombotic Disorders; found in Bb under assignments button in the lecture admission tickets folder. Due 11/26/2024
  • Pre-Lab Assessment: D-dimer; found in Bb under the Assignments button in the Pre-Lab folder. Due 11/26/2024
  • Complete MLAB 1227 Course Evaluation

11/26/2024

Topic
Textbook
  • Ch. 39, pp. 761-782
    • Thrombotic Disorders and Lab Assessment
  • Ch. 41, pp. 831-832 (D-dimer)
    • Laboratory Evaluation of Hemostasis
Laboratory
Assignment
  • Thrombophilia Crossword.
    • Navigate to the “Dropbox” in Bb, select the “Homework” folder, upload assignment.
    • Due 12/1/2024 

12/4/2024

Topic
  • TBA
Textbook
Laboratory
  • Lab Practical
Assignment

12/5/2024

Topic
  • Course Final Exam
Textbook
Laboratory
Assignment

12/11/2024

Topic
  • Study for Fall Capstone
Textbook
Laboratory
Assignment

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